PUBLICATIONS FROM PROJECTS FUNDED BY THE LMI
2013
First International Conference on Generalized Lymphatic Anomaly and Gorham–Stout Syndrome
Dellinger et al., 2013. IBMS BoneKEy 10; Article number:476.
2014
Kaposiform Lymphangiomatosis: A Distinct Aggressive Lymphatic Anomaly
Croteau et al., 2014. J Pediatr 164;383-388.
http://www.ncbi.nlm.nih.gov/pubmed/24252784
Viewpoints on vessels and vanishing bones in Gorham-Stout disease.
Dellinger et al., 2014. Bone 63;47-52.
http://www.ncbi.nlm.nih.gov/pubmed/24583233
Pulmonary Lymphangiectasia Resulting from Vegf-C Overexpression During a Critical Period.
Yao et al., 2014. Circ Res 114;806-822.
http://www.ncbi.nlm.nih.gov/pubmed/24429550
2015
Caution is recommended prior to sildenafil use in vascular anomalies.
Rankin et al., 2015. Pediatr Blood Cancer 62;2015-2017.
http://www.ncbi.nlm.nih.gov/pubmed/25982365
Near-Infrared Fluorescence Lymphatic Imaging in Lymphangiomatosis.
Rasmussen et al., 2015. Lymphat Res Biol 13;195-201.
http://www.ncbi.nlm.nih.gov/pubmed/26287470
2016
Pulmonary and pleural lymphatic endothelial cells from pediatric, but not adult, patients with Gorham-Stout disease and generalized lymphatic anomaly, show a high proliferation rate.
Mori et al., 2016. Orphanet J Rare Dis.11:67.
https://www.ncbi.nlm.nih.gov/pubmed/27194137
Meeting report for the 2016 conference on GLA and Gorham-Stout disease
Iacobas et al., 2016. IBMS BoneKEy.
A New Case and Review of Chylothorax in Generalized Lymphatic Anomaly and Gorham-Stout Disease.
Ludwig et al., 2016. Lymphology. 49;73-84.
https://www.ncbi.nlm.nih.gov/pubmed/29906363
2017
Rapamycin reversal of VEGF-C-driven lymphatic anomalies in the respiratory tract.
Baluk et al., 2017. JCI Insight. 2017 Aug 17;2(16). pii: 90103
https://www.ncbi.nlm.nih.gov/pubmed/28814666
Lymphatic Endothelial Cells Produce M-CSF, Causing Massive Bone Loss in Mice.
Wang et al., 2017. J Bone Miner Res. 32;939-950.
https://www.ncbi.nlm.nih.gov/pubmed/28052488
Angiopoietins as serum biomarkers for lymphatic anomalies.
Le Cras et al., 2017. Angiogenesis. 20;163-173.
https://www.ncbi.nlm.nih.gov/pubmed/27990590
2018
VEGF-C promotes the development of lymphatics in bone and bone loss.
Hominick et al., 2018. eLife 2018;7:e34323
https://www.ncbi.nlm.nih.gov/pubmed/29620526
2019
Somatic activating mutations in PIK3CA cause generalized lymphatic anomaly.
Rodriguez-Laguna et al., 2019 Journal of Experimental Medicine. 216;407-418.
https://www.ncbi.nlm.nih.gov/pubmed/30591517
Signaling pathways and inhibitors of cells from patients with kaposiform lymphangiomatosis.
Boscolo et al., 2019. Pediatr Blood Cancer. Aug;66(8):e27790.
https://www.ncbi.nlm.nih.gov/pubmed/31045327
2020
Kaposiform lymphangiomatosis treated with multimodal therapy improves coagulopathy and reduces blood angiopoietin-2 levels.
Crane J, et al., 2020. Pediatr Blood Cancer. Jul 7:e28529.
https://pubmed.ncbi.nlm.nih.gov/32634277/
Constitutively active PIK3CA mutations are expressed by lymphatic and vascular endothelial cells in capillary lymphatic venous malformation.
Le Cras et al., 2020. Angiogenesis. 23;425-442.
https://pubmed.ncbi.nlm.nih.gov/32350708/
Lymphatics in bone arise from pre-existing lymphatics.
Monroy et al., 2020. Development. 2020 Apr 20;147(21):dev184291.
https://pubmed.ncbi.nlm.nih.gov/32188632/
Multidisciplinary guidelines for initial evaluation of complicated lymphatic anomalies-expert opinion consensus.
Iacobas et al., 2020. Pediatr Blood Cancer. Jan;67(1):e28036.
https://pubmed.ncbi.nlm.nih.gov/31617676/
Abnormal Pulmonary Lymphatic Flow in Patients With Lymphatic Anomalies and Respiratory Compromise.
Itkin et al., 2020. Chest. Mar 24:S0012-3692(20)30474-8. doi: 10.1016/j.chest.2020.02.058. PMID: 32220591
https://pubmed.ncbi.nlm.nih.gov/32220591/