Previous Projects


Investigator: Shoshana Greenberger
Institution: Sheba Medical Center
Title of Project: Vertebrate based model for targeting overactivation of nras pathway in GLA

Investigator: Mike Dellinger
Institution: UT Southwestern Medical Center
Title of Project: Development and characterization of an animal model of Gorham-Stout disease

Investigator: Erik Eklund
Institution: Lund University
Title of Project: Immunohistochemical features of lymphangiomatosis and Gorham’s disease

Investigator: Ionela Iacobas
Institution: Baylor College of Medicine
Title of Project: Lymph-loss Markers as Predictors of Severity in Generalized Lymphatic Anomaly and Gorham-Stout Disease

Investigator: Donald McDonald
Institution: University of California, San Francisco
Title of Project: Transgenic mouse model to determine the mechanism and treatment of congenital pulmonary lymphangiectasia and lymphangiomatosis

Investigator: Ramani Ramchandran
Institution: Medical College of Wisconsin
Title of Project: Molecular crosstalk and matrix metalloproteinases in generalized lymphatic anomaly (GLA) and gorham-stout syndrome (GSS) patients

Investigator: Eva Sevick
Institution: UT Health Science Center at Houston
Title of Project: Imaging lymphatic function in normal subjects and persons with lymphatic disorders

Investigator: Cameron Trenor
Institution: Boston Children’s Hospital
Title of Project: Lymphatic anomalies database

Investigator: Lianping Xing
Institution: University of Rochester
Title of Project: Bone cells and lymphatic endothelium interface

 

MILLION DOLLAR BIKE RIDE PROJECTS

 

 

2016

 

Investigators: Maxim Itkin and Yaov Dori
Institution: University of Pennsylvania
Title of Project: Dynamic Contrast Enhanced MR Lymphangiogram Imaging of Lymphatic Anomalies

Investigator: David Cormode
Institution: University of Pennsylvania
Title of Project: Nano-magnetic Oils for the Study of Intestinal Lymphatics in Lymphangiomatosis

Investigator: Joseph Rutkowski,
Institution: Texas A&M Health Science Center School of Medicine
Title of Project: Inducible Lymphatic Hyperplasia to Drive Chylous Accumulation Mimicking Lymphangiomatosis

 

2017

 

Investigator: Andrea Del Fattore, and Andrea Bartuli
Institution: Bambino Gesù Children’s Hospital, Rome, Italy
Title of Project: Understanding the molecular and cellular defects of bone remodeling in patients affected by Gorham-Stout disease (GSD)

Investigator: Carrie Shawber
Institution: Columbia University Medical Center
Title of Project: Identification of the Genetic Causes of Generalized Lymphatic Anomalies

 

2018

 

Investigator: J. Brandon Dixon
Institution: Georgia Tech
Title of Project: Tissue Engineered Lymphatic Malformation on a Chip for Screening Therapeutics

Investigator: Denise Adams
Institution: Boston Children’s Hospital
Title of Project: Retrospective analysis of the safety and efficacy of lymphatic anomalies of the bone (Generalized Lymphatic anomaly (GLA), Gorham Stout Disease (GSD), Channel type Lymphatic Malformation (CTLM)) treated with mTOR inhibition and bisphosphonates